Yes, that's what I use, so I've never even seen the ads you're talking about.
If you meet the minimal requirements: Firefox 2.0, Thunderbird 2.0, SeaMonkey 1.1, Flock 1.0, Songbird 0.7, eMusic Remote 1.0, Prism 0.9, then head on over to http://adblockplus.org It's absolutely wonderful!