GNOME for Windows is possible, using the Cygwin that is used in de KDE port for Windows and works very well. There is some old version that are ported (1.4 oooold). The Cygnome project is working to port the 2.x version. If Dia, GIMP, Gvim works fine on Windows why Gnome dont?
My fav distro is Fedora, i switch to this after the Mandrake power off.
Fedora is a very stable distro, with only open source software, but you can use other software (mp3, nvidia, wma) with some extras repos.
Is totally created by the fedoraproject (not for a company (Novell, Canonical))
Has one of the best developer envirionment (ext4 was developed and tested in Fedora). The kernel is very small, and runs very well, because, compile and load essential modules, (Ubuntu: NO everybody needs the NinjaMP3 FileSystem Driver).
The configuration is easy like all the others distros (like Ubuntu) just has the problem that only includes open source software and some drivers aren't available. But sometimes users only need add modules.