How to make a slide? To create slide firstly Open the PowerPoint program. Powerpoint automatically opens a new presentation. A new title slide will appear for you to work with. Then to create a new presentation in the Open window, click the Microsoft Office Button. From the drop-down list, select New. After that The New window will appear. Blank and recent is automatically highlighted in the list of options on the left. Click Create. A new Blank Presentation template will open with a new Title Slide in the Slide Layout view. Then If you don't want the Title Slide layout, you can easily change it to one of the other available layouts. All the slide layouts you can choose from will appear. Click on whichever one you want to use. The slide layout is now changed.