Chrome is nice and fast but lacks a lot of funcionality in most sites i am member. For example, a few "blog" sites will not show me the toolbars i need to edit my posts and blogs. I do like the fact that if one browserwindow crashes the other windows are not affected by it.
Currently i use chrome for sites that i don't need and adressbar for (like my chatbox on my forum) and that i want to have quick access too, the shortcut option it provides is a very great tool for this
i love chrome, i use firefox for when i need to use a extension, but chrome almost never crashes and i was using FF 3 and it would keep getting up into the 300K memory use with only 2 tabs (facebook, x10) but when im using chrome its at like 75K
Google Chrome is good for use of speed and games. But when it comes to work and other stuff this will not work for you because of usability and compatible is going to be an issue.