**shudders** Word and Frontpage both insert loads of random crap in the page. I'd suggest starting with either, then examining the html and working out what you don't need, so you can strip it out. As a clue, the basic web page should be in the following form
HTML:
<html>
<head>
<title>My Web Page</title>
</head>
<body>
My content
</body>
</html>
Usually you will find loads of extra junk in the head section that you can remove (though you might want to keep <style> and <link...>). Comments
HTML:
<!-- everything in here -->
can be removed without a second thought.
Also, what Word tends to do is things like:
HTML:
<o:p></o:p>
and
<p class=MsoNormal></p>
These are redundant as there is nothing between the tags - so remove them!